DMC1 encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. DNA meiotic recombinase 1, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. 蛋白别名为:DMC1; DMC1H; LIM15; Meiotic recombination protein DMC1/LIM15 homolog;基因ID为:11144;蛋白质ID:Q14565
应用类型
IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human Dmc1. at AA rangle: 30-110