POLD3 encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The DNA polymerase delta 3, accessory subunit plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene.蛋白别名为:POLD3; KIAA0039; DNA polymerase delta subunit 3; DNA polymerase delta subunit p66;基因ID为:10714;蛋白质ID:Q15054
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human DNA pol δ3. at AA rangle: 380-460