TREM1 encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. Triggering receptor expressed on myeloid cells 1 amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.蛋白别名为:TREM1; Triggering receptor expressed on myeloid cells 1; TREM-1; Triggering receptor expressed on monocytes 1; CD354;基因ID为:54210;蛋白质ID:Q9NP99
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-300 ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human TREM-1. at AA rangle: 40-120