DNA repair protein XRCC4 encoded by XRCC4 functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.蛋白别名为:XRCC4; DNA repair protein XRCC4; X-ray repair cross-complementing protein 4;基因ID为:7518;蛋白质ID:Q13426
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human XRCC4. at AA rangle: 230-310