SOX8 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The transcription factor SOX-8 may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).蛋白别名为:SOX8; Transcription factor SOX-8; SOX9; Transcription factor SOX-9; SOX17; Transcription factor SOX-17; SOX18; Transcription factor SOX-18;基因ID为:30812/6662/64321/54345;蛋白质ID:P57073/P48436/Q9H6I2/P35713
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human Sox-8/9/17/18. at AA rangle: 90-170