Pre-mRNA splicing occurs in 2 sequential transesterification steps. Pre-mrna processing factor 18 encoded by PRPF18is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. Pre-mrna processing factor 18 as a sequence similarity to the yeast splicing factor Prp18.蛋白别名为:PRPF18; HPRP18; Pre-mRNA-splicing factor 18; PRP18 homolog; hPRP18;基因ID为:8559;蛋白质ID:Q99633
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human PRPF18. at AA rangle: 160-240