Phosphodiesterase 4C encoded by PDE4C belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, phosphodiesterase 4C plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for PDE4C.蛋白别名为:PDE4C; DPDE1; cAMP-specific 3'; 5'-cyclic phosphodiesterase 4C; DPDE1; PDE21;基因ID为:5143;蛋白质ID:Q08493
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human PDE4C. at AA rangle: 260-340