The tumor suppressor WT1 represses and activates transcription. Pro-apoptotic WT1 regulator encoded by PAWR is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. Pro-apoptotic WT1 regulator is specifically upregulated during apoptosis of prostate cells.蛋白别名为:PAWR; PAR4; PRKC apoptosis WT1 regulator protein; Prostate apoptosis response 4 protein; Par-4;基因ID为:5074;蛋白质ID:Q96IZ0
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human PAR4. at AA rangle: 260-340