Mammalian mitochondrial ribosomal protein L 20 (39S ribosomal protein L20 mitochondrial) is encoded by nuclear gene MRPL20 and help in protein synthesis within the mitochondrion.Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 21q. Alternative splicing results in multiple transcript variants encoding different isoforms.蛋白别名为:MRPL20; 39S ribosomal protein L20; mitochondrial; L20mt; MRP-L20;基因ID为:55052;蛋白质ID:Q9BYC9
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human MRP-L20. at AA rangle: 80-160