Mammalian mitochondrial ribosomal protein L 12 (39S ribosomal protein L12 mitochondrial) is encoded by nuclear gene MRPL12 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex.蛋白别名为：MRPL12; RPML12; 39S ribosomal protein L12; mitochondrial; L12mt; MRP-L12; 5c5-2;基因ID为：6182；蛋白质ID:P52815
应用类型
WB，ELISA补充：最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽：the Internal region of human MRP-L12. at AA rangle: 1-80
