Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. HK1 encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in HK1 have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.蛋白别名为:HK1; Hexokinase-1; Brain form hexokinase; Hexokinase type I; HK I;基因ID为:3098;蛋白质ID:P19367
应用类型
WB,IHC-p,IF,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the N-terminal region of human HXK I. at AA rangle: 1-80