HBP1 is a Protein Coding gene. HMG-Box Transcription Factor 1 is a transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5-TTCATTCATTCA-3. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. Among its related pathways are C-MYC pathway and Regulation of Wnt-mediated beta catenin signaling and target gene transcription. GO annotations related to this gene include RNA binding.蛋白别名为:HBP1; HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1;基因ID为:26959;蛋白质ID:O60381
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human HBP1. at AA rangle: 400-480