Glutathione S-transferase theta-1 encoded by GSTT1 is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1, GSTT2, and GSTT2B. GSTT1 and GSTT2/GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis. The GSTT1 gene is haplotype-specific and is absent from 38% of the population. Alternative splicing of this gene results in multiple transcript variants. 蛋白别名为:GSTT1; Glutathione S-transferase theta-1; GST class-theta-1; Glutathione transferase T1-1; GSTT4; Glutathione S-transferase theta-4; GST class-theta-4;基因ID为:2952;蛋白质ID:P30711/A8MPT4
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the N-terminal region of human GSTT1/4. at AA rangle: 10-90