Melatonin-related receptor belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of GPR50 have been associated with bipolar affective disorder in women. 蛋白别名为:GPR50; Melatonin-related receptor; G protein-coupled receptor 50; H9;基因ID为:9248;蛋白质ID:Q13585
应用类型
WB,IF,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IF: 1:200-1:1000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human GPR50. at AA rangle: 270-350