GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. Beta-1,4 N-acetylgalactosaminyltransferase 1 is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. Beta-1,4 N-acetylgalactosaminyltransferase 1 catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene. 蛋白别名为:B4GALNT1; GALGT; SIAT2; Beta-1; 4 N-acetylgalactosaminyltransferase 1; (N-acetylneuraminyl)-galactosylglucosylceramide; GM2/GD2 synthase; GalNAc-T;基因ID为:2583;蛋白质ID:Q00973
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human GM2/GD2 synthase. at AA rangle: 250-330