Fas-activated serine/threonine kinase encoded by FASTK is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. 蛋白别名为：FASTK; Fas-activated serine/threonine kinase; FAST kinase;基因ID为：10922；蛋白质ID:Q14296
应用类型
WB，ELISA补充：最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000. Immunocytochemistry: 1:200-1:1000, ELISA: 1:10000. Not yet tested in other applications.
