The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. DCAMKL3 (doublecortin-like and CAM kinase-like 3), also known as DCLK3 or DCDC3C, is a 648 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one protein kinase domain. One of several members of the Ser/Thr protein kinase family, DCAMKL3 functions to catalyze the ATP-dependent attachment of a phospho residue to target proteins, an event that may play a role in various cellular processes.蛋白别名为:DCLK3; DCAMKL3; DCDC3C; KIAA1765; Serine/threonine-protein kinase DCLK3; Doublecortin domain-containing protein 3C; Doublecortin-like and CAM kinase-like 3; Doublecortin-like kinase 3;基因ID为:85443;蛋白质ID:Q9C098
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human DCAMKL3. at AA rangle: 260-340