CAP-Gly domain containing linker protein 2 encoded by CLIP2 belongs to the family of cytoplasmic linker proteins, which have been proposed to mediate the interaction between specific membranous organelles and microtubules. This protein was found to associate with both microtubules and an organelle called the dendritic lamellar body. CLIP2 is hemizygously deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.蛋白别名为:CLIP2; CYLN2; KIAA0291; WBSCR3; WBSCR4; WSCR4; CAP-Gly domain-containing linker protein 2; Cytoplasmic linker protein 115; CLIP-115; Cytoplasmic linker protein 2; Williams-Beuren syndrome chromosomal region 3 protein; Williams-Beuren syndro;基因ID为:7461;蛋白质ID:Q9UDT6
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human CLIP-115. at AA rangle: 960-1040