CLCNKA is a member of the CLC family of voltage-gated chloride channels. The encoded protein(chloride voltage-gated channel Ka)is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for CLCNKA.蛋白别名为:CLCNKA; Chloride channel protein ClC-Ka; Chloride channel Ka; ClC-K1;基因ID为:1187;蛋白质ID:P51800
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human CLC-KA. at AA rangle: 550-630