The protein(glucosylceramidase beta 3 (gene/pseudogene))encoded by GBA3 is an enzyme that can hydrolyze several types of glycosides. GBA3 is a polymorphic pseudogene, with the most common allele being the functional allele that encodes the full-length protein. Some individuals, as represented by the reference genome allele, contain a single nucleotide polymorphism that results in a premature stop codon in the coding region, and therefore this allele is pseudogenic due to the failure to produce a functional full-length protein. Alternative splicing of GBA3 results in multiple transcript variants.蛋白别名为:GBA3; CBG; CBGL1; Cytosolic beta-glucosidase; Cytosolic beta-glucosidase-like protein 1;基因ID为:57733;蛋白质ID:Q9H227
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human CBG. at AA rangle: 260-340