CACNA2D4 encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of CACNA2D4 have been observed but have not been thoroughly characterized. 蛋白别名为:CACNA2D4; Voltage-dependent calcium channel subunit alpha-2/delta-4; Voltage-gated calcium channel subunit alpha-2/delta-4;基因ID为:93589;蛋白质ID:Q7Z3S7
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human Cacna2d4. at AA rangle: 520-600