The protein encoded by CEBPE is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein(CCAAT/enhancer binding protein epsilon)may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. 蛋白别名为:CEBPE; CCAAT/enhancer-binding protein epsilon; C/EBP epsilon;基因ID为:1053;蛋白质ID:Q15744
应用类型
WB,IHC-p,IF,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:5000. Not yet tested in other applications.
免疫原
合成多肽:human C/EBP ε around the non-phosphorylation site of T74.