The specific function of ACTR3 has not yet been determined; however, the protein(ARP3 actin related protein 3 homolog) it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Three transcript variants encoding two different isoforms have been found for ACTR3.蛋白别名为:ACTR3; ARP3; Actin-related protein 3; Actin-like protein 3;基因ID为:10096;蛋白质ID:P61158
应用类型
WB,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human Arp3. at AA rangle: 340-420