SLC25A12 encodes a calcium-binding mitochondrial carrier protein. The encoded protein(solute carrier family 25 member 12) localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in this gene may be associated with autism, and mutations in SLC25A12 may also be a cause of global cerebral hypomyelination. Alternatively spliced transcript variants have been observed for SLC25A12.蛋白别名为:SLC25A12; ARALAR1; Calcium-binding mitochondrial carrier protein Aralar1; Mitochondrial aspartate glutamate carrier 1; Solute carrier family 25 member 12;基因ID为:8604;蛋白质ID:O75746
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human ARALAR. at AA rangle: 360-440