Acyl-CoA synthetase long-chain family member 6 encoded by ACSL6 catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for ACSL6. 蛋白别名为:ACSL6; ACS2; FACL6; KIAA0837; LACS5; Long-chain-fatty-acid--CoA ligase 6; Long-chain acyl-CoA synthetase 6; LACS 6;基因ID为:23305;蛋白质ID:Q9UKU0
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human ACSL6. at AA rangle: 470-550