ACAT1 encodes a mitochondrially localized enzyme(acetyl-CoA acetyltransferase 1) that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in ACAT1 are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.蛋白别名为:ACAT1; ACAT; MAT; Acetyl-CoA acetyltransferase; mitochondrial; Acetoacetyl-CoA thiolase; T2;基因ID为:38;蛋白质ID:P24752
应用类型
WB,IHC-p,ELISA补充:最优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:40000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human ACAT-1. at AA rangle: 190-270