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中文名称

Arginase I, Human Liver-Type BioAssay ELISA Kit

英文名字
Arginase I, Human Liver-Type BioAssay ELISA Kit
供应商
USBiological
产品货号
A3340-14
产品报价
¥1/1Kit
产品说明书
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背景资料
USBiological品牌是全球有名的抗原抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。武汉艾美捷科技作为USBiological品牌中国区域总代理,是行业中少有的致力于服务客户,帮助客户,且拥有独立的专业销售团队、技术支持团队、市场营销团队、进出口报关团队的高科技生物企业。可以为您提供及时的咨询响应,专业的产品和解决方案支持,稳健快捷的交货周期,优质放心的售后服务。我们致力于为您提供有价值的产品和服务,在意您的成功!
产品描述
This ELISA is a sandwich enzyme immunoassay for the quantitative measurement of human liver-type arginase in serum and cerebrospinal fluid (CSF). It is intended for in vitro and research use.Arginase [EC 3.5.3.1; L-arginine aminohydrolase] is an enzyme that hydrolyzes L-arginine to L-ornithine and urea in the urea cycle. Two forms of arginase exist which are designated arginase I and arginase II. Liver-type arginase I is expressed primarily in the liver and to some extent in the erythrocytes. Arginase II is expressed in many extrahepatic tissues such as the brain, spinal cord, kidney, small intestine, and mammary gland. Although arginase I and arginase II have similar enzyme activities, they have different pI, immunological reactivity and are encoded by different genes. Human arginase I is a 35kD protein circulating in blood probably as a homotrimer.Circulating liver-type arginase was clinically used as a liver specific marker which may reflect not only early occurrence of liver injury but also early termination of liver injury. The measurement of liver-type arginase is clinically applicable for monitoring conditions of patients with liver disorders or pre- and postoperative conditions of patients who received partial hepatectomy with quicker normalization in comparison with aminotransferases (ALT and AST). Recently, the arginase I gene was found to be one of the most prominent among asthma genes. In situ hybridization demonstrated marked staining of arginase I in submucosal inflammatory lesions and arginase activity increased in allergen-challenged lungs. Finally, it was found that arginase I was the most significantly up-regulated protein in the murine spinal cord during experimental autoimmune encephalomyelitis. The results indicated that arginase I played important roles in autoimmune inflammation in the central nervous system.Time: <3 hours.Range: 5-320ng/mlSensitivity: 0.027ng/mlKit Components:A3340-14F: Microtiter Plate, 1x96 wells Coated with capture Anti-Arginase Antibody,A3340-14G: Mab (HRP), 1x13ml*A3340-14H: Calibrator, 2x 1 vialA3340-14L: Standard Diluent,1x2mlA3340-14M: Dilution Buffer, 1x13mlA3340-14N: Wash Buffer, 10X ,1x100mlA3340-14P: Substrate (TMB) Solution, 1x13mlA3340-14Q: Stop Solution (0.2M H2SO4), 1x13mlStorage and Stability:Store *A3340-14H at -20°C. Store other components at 4°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
产品特点
针对Arginase I, Human Liver-Type BioAssay ELISA Kit该产品的特点优势,欢迎查阅官网提供的产品说明书。
保存建议
建议收到Arginase I, Human Liver-Type BioAssay ELISA Kit产品后将其置于4°C/-20°C保存。
其他
Usbiological公司是美国著名的抗体和生化试剂供应商,生产世界上种类最多的抗体,用于Western Blot、免疫沉淀、免疫荧光、免疫组化和流式细胞术等多种检测方法。Usbiological公司现已拥有超过50,19234种抗体、抗原和生化产品,为科研用户提供了诸多超值选择。
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