The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon，and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
应用类型
ICC: 1:200-1:1000, Western Blot: 1:1000-1:2000, IHC: 1:500-1:2000
免疫原
A peptide corresponding to residues near the N-terminus of human BAG-1L
