EphA2 a receptor tyrosine kinase. Receptor for members of the ephrin-A family. Binds to ephrin-A1，-A3，-A4 AND -A5. The Eph receptor tyrosine kinase family，the largest in the tyrosine kinase group，has fourteen members. They bind membrane-anchored ligands，ephrins，at sites of cell-cell contact，regulating the repulsion and adhesion of cells that underlie the establishment，maintenance，and remodeling of patterns of cellular organization. Eph signals are particularly important in regulating cell adhesion and cell migration during development，axon guidance，homeostasis and disease.
应用类型
Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blotting, ELISA
免疫原
A synthesized peptide derived from human EPHA2/3/4 around the phosphorylation site of Tyrosine 588 and 596.
