BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throμghout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name，BMPs initiate，promote and regulate bone development，growth，remodeling and repair. In addition to its osteogenic activity，BMP-2 plays an important role in cardiac morphogenesis. It is also expressed in a variety of tissues such as lung，spleen，brain，liver，prostate ovary and small intestine.
应用类型
WB, IHC
免疫原
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BMP2
