EpCAM is a Mr 40,000,type I transmembrane glycoprotein that consists of two epidermal growth factor-like extracellularndomains,a cysteine-poor region,a transmembrane domain,and a short cytoplasmic tail. EpCAM is encoded by the GA733-2ngene located on the long arm of chromosome 4. EpCAM has been described by various names,including those associated withnmonoclonal antibodies specific for the cell surface antigen (MH99,AUA1,MOC31,323/A3,KS1/4,GA733,and HEA125) andncDNA clones used to define the antigen KS 1/4,EGP,EGP40,and GA733-2.
应用类型
WB, IHC
免疫原
A partial length recombinant human EpCAM (amino acids 110-314) was used as the immunogen