Rab5 is a small GTPase belonging to Ras superfamily of monomeric G proteins. Rab GTPases play an essential role in the regulation of membrane traffic and are involved in vesicle formation and trasport and fusion to the membrane. Rab5 is expressed on exosome membranes and it might have an active role during endo/exocytotic processes of microvesicles through the plasma membrane.
