CD15 plays a role in mediating phagocytosis，bactericidal activity，and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition，CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.
应用类型
FC, IF, IHC
免疫原
Purified human neutrophils (FUT4/815); Myelomonocytic leukemia cells (BRA-4F1)
