This antibody recognizes proteins of 80-200 kDa,identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands,stroma,or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung,colon,stomach,esophagus,pancreas,gallbadder,urachus,salivary gland,ovary,and endocervix.
应用类型
FC, IF, IHC
免疫原
Recombinant full-length human CEA protein (C66/195; C66/261; C66/1009 & C66/1030)
来源宿主
提供的抗癌胚抗原,泛型抗体(鸡尾酒)Anti-Carcinoembryonic Antigen, pan Antibody (Cocktail)产品,该来源宿主查看产品说明书。