Recognizes a glycoprotein of ~200 kDa,identified as carbonic anhydrase IX (CAIX/gp200). Carbonic Anhydrases (CAs) are members of a large family of zinc metallo-enzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes,including respiration,calcification,acid-base balance,bone resorption and the formation of aqueous humor,cerebrospinal fluid,saliva and gastric juice. They show extensive diversity in distribution and in their subcellular localization. CA IX is specifically expressed in clear-cell renal carcinomas.
应用类型
FC, IF, IHC, WB
免疫原
Recombinant human CA9 protein
来源宿主
提供的抗碳酸酐酶IX抗体(CA9/781)Anti-Carbonic Anhydrase IX Antibody (CA9/781)产品,该来源宿主查看产品说明书。