Recognizes a protein of 27 kDa,identified as the Bcl-X protein. This MAb shows no cross-reaction with Bcl-2 or Bax protein. Bcl-X has two isoforms,Bcl-XL (long),a 241 amino acid protein which suppresses cell death. And Bcl-XS (short),a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2. This MAb reacts with both Bcl-XS and Bcl-XL proteins.
应用类型
FC, IF, IHC, WB
免疫原
A synthetic peptide, aa 3-14 (Cys-QSNRELVVDFLS) of human Bcl-X protein