This antibody recognizes an oncofetal glycoprotein with a single chain of 70 kDa，which is identified as alpha-fetoprotein (AFP) (ISOBM TD-2 workshop). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver，intestinal tract，and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms，especially yolk sac tumors.
应用类型
FC, IF, IHC
免疫原
Alpha fetoprotein (AFP) purified from serum of a hepatoma patient
