Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm.
应用类型
WB, IF
免疫原
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human DCLK2
