Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division，and participates in the regulation of glycogen metabolism，muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex，which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
应用类型
WB, IF, IHC
免疫原
Recombinant human PPP1A protein expressed in E.coli
