Acts as a transcriptional activator Binds to the DNA consensus sequence 5'-GACCACCCA-3'. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development,as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling. Plays a role in cell proliferation and differentiation via its role in SHH signaling
应用类型
WB
免疫原
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GLI1