Protein derived from the fusion of a methylase with the transposase of an Hsmar1 transposon that plays a role in DNA double-strand break repair，stalled replication fork restart and DNA integration. DNA-binding protein，it is indirectly recruited to sites of DNA damage through protein-protein interactions. Has also kept a sequence-specific DNA-binding activity recognizing the 19-mer core of the 5'-terminal inverted repeats (TIRs) of the Hsmar1 element and displays a DNA nicking and end joining activity
应用类型
WB, IH
免疫原
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SETMAR
