This gene encodes a member of the Rho GTPase-activator protein superfamily. The encoded protein may function as a Rho GTPase-activating protein. Alterations in this gene may be associated with several diseases,including rheumatoid arthritis,celiac disease,and multiple sclerosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. May function as a GTPase-activating protein and may play important roles during T-cell activation.
应用类型
WB, IH
免疫原
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TAGAP