May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping the tail of ITGB1. Seems to be involved in mammary cell migration. May be involved in cell migration and bone development.
应用类型
WB, IH, IF/IC
免疫原
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Tensin 3
