Integrin alpha-L/beta-2 is a receptor for ICAM1,ICAM2,ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction,cytotoxic T-cell mediated killing,and antibody dependent killing by granulocytes and monocytes.
应用类型
抗CD11a(依法珠单抗),人类IgG1抗体Anti-CD11a (Efalizumab), Human IgG1 Antibody该产品的应用类型查阅产品说明书。
免疫原
Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.