BCAT1，also known as branched chain amino-acid transaminase (cytosolic form)，catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. BCAT1 is expressed in the brain and kidney. Overexpressed in MYC-induced tumors such as Burkitt's lymphoma.
应用类型
Western blot, ELISA
免疫原
Recombinant human BCAT1 (1-386aa) purified from E. coli
