EDG4 is a member of family I of the G protein-coupled receptors，as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization，a critical cellular response to LPA in cells，through association with Gi and Gq proteins. It plays a key role in phospholipase C-beta (PLC-beta) signaling pathway and stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation.
应用类型
Western blot, IHC
免疫原
KLH conjugated synthetic peptide between 3-32 amino acids from the N-terminal region of human EDG4
