The protein encoded by TNNT2 is the tropomyosin-binding subunit of the troponin complex,which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms,however,the full-length nature of some of these variants has not yet been determined.
应用类型
WB, ELISA, IHC
免疫原
肌钙蛋白T单克隆抗体Troponin T Monoclonal Antibody该产品的免疫原查阅产品说明书。