This gene encodes a member of the sorting nexin family.
Members of this family contain a phox (PX) domain, which is a
phosphoinositide binding domain, and are involved in intracellular
trafficking. This endosomal protein regulates the cell-surface
expression of epidermal growth factor receptor. This protein also
has a role in sorting protease-activated receptor-1 from early
endosomes to lysosomes. This protein may form oligomeric complexes
with family members. This gene results in three transcript variants
encoding distinct isoforms.
