The protein encoded by this gene catalyzes the conversion
of L-lactate and NAD to pyruvate and NADH in the final step of
anaerobic glycolysis. The protein is found predominantly in muscle
tissue and belongs to the lactate dehydrogenase family. Mutations
in this gene have been linked to exertional myoglobinuria. Multiple
transcript variants encoding different isoforms have been found for
this gene. The human genome contains several non-transcribed
pseudogenes of this gene.