This gene encodes the soluble mannose-binding lectin or
mannose-binding protein found in serum. The protein encoded belongs
to the collectin family and is an important element in the innate
immune system. The protein recognizes mannose and
N-acetylglucosamine on many microorganisms, and is capable of
activating the classical complement pathway. Deficiencies of this
gene have been associated with susceptibility to autoimmune and
infectious diseases.
